Researchers identify a psychedelic-like drug without the hallucinogenic side effects

Psychedelic drugs have shown promise for treating neuropsychiatric disorders like depression and posttraumatic stress disorder. However, due to their hallucinatory side effects, some researchers are trying to identify drugs that could offer the benefits of psychedelics without causing hallucinations. Researchers now report they have identified one such drug through the development of a genetically encoded fluorescent sensor -- called psychLight -- that can screen for hallucinogenic potential.
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Astronauts’ mental health risks tested in the Antarctic

Astronauts who spend prolonged time alone in space face mental health stressors like loneliness, isolation and more. A psychologist developed the Mental Health Checklist, a self-reporting instrument for detecting mental health changes in isolated, confined, extreme environments. She's reporting results that show significant declines in positive emotions.
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Psychedelic experience may not be required for psilocybin’s antidepressant-like benefits

Researchers have shown that psilocybin -- the active chemical in 'magic mushrooms' -- still works its antidepressant-like actions, at least in mice, even when the psychedelic experience is blocked. The new findings suggest that psychedelic drugs work in multiple ways in the brain and it may be possible to deliver the fast-acting antidepressant therapeutic benefit without requiring daylong guided therapy sessions.
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