The Gerson regimen does not treat or prevent cancer.
The Gerson regimen was developed by Max Gerson in the 1940s. It involves a strict metabolic diet that emphasizes fresh fruit and vegetable juice, high carbohydrate and potassium, no sodium or fat, and low animal protein. The diet is often supplemented with digestive enzymes, coffee enemas, and various supplements, including laetrile. This diet is based on the theory that it addresses the cause of cancer by detoxifying the body and stimulating metabolism so that the body can heal itself. These toxins, Gerson claimed, build up from environmental pollution and processed foods and eventually alter cell metabolism. However, this proposed toxin build-up has never been proven, nor has the diet’s ability to remove such toxins from the body.
Coffee enemas are used in several metabolic therapies. Theoretically, coffee enemas might aid excretion from the liver and colon, but no theory has been proven. In addition, coffee enemas can be dangerous when used repeatedly, causing electrolyte imbalances in the blood and impaired nutrient absorption. Because the high levels of fruits and vegetables are eaten raw, they may not be absorbed as easily, especially in patients with GI cancers or chemotherapy-induced GI disorders.
Purported Uses
There is no scientific evidence to support use of Gerson regimen for the following:
To manage allergies and asthma
To treat arthritis
To treat atherosclerosis
To treat cancer
To treat heart disease
To treat chronic fatigue syndrome
To detoxify the body
To treat diabetes
To lower high blood pressure
To treat infertility
To treat Lou Gehrig’s Disease
To treat migraine headaches
To treat multiple sclerosis
To treat peptic ulcers
To treat psoriasis
To treat tuberculosis
Patient Warnings
The American Cancer Society warns that Gerson therapy can be very harmful to the body.
Metabolic diets like the Gerson Regimen can result in nutrient deficiencies (calcium, vitamins D and B12, protein), anemia, and malabsorption in the intestine.
Side Effects
Flu-like symptoms
Loss of appetite
Perspiration with foul odor
Weakness, dizziness
Cold sores, fever blisters
High fever
Tumor pain
Intestinal cramping, diarrhea, and vomiting
Coffee enemas, a regular part of the Gerson regimen, can cause electrolyte imbalance, which has resulted in serious infections, dehydration, colitis, constipation, seizures, pleural and pericardial effusions (fluid collecting in the lining around the lungs and heart), and death.
Coma from low sodium levels in the blood has occurred in a handful of patients.
Clinical Summary
Regimen developed by Max Gerson involving a strict metabolic diet, coffee enemas, and various supplements, including laetrile, which is illegal in the United States but available at clinics in Mexico and elsewhere. The diet emphasizes fresh fruit and vegetable juice, high carbohydrate and potassium, no sodium or fat, and low animal protein, and is sometimes supplemented with exogenous digestive enzymes. This regimen claims to address the cause of cancer by detoxifying the system and stimulating metabolism so that the body can heal itself (10).
Coffee enemas can cause infections, dangerous electrolyte deficiencies, and death (5). Despite proponents’ claims of recovery rates as high as 70-90 percent, case reviews by the NCI and New York County Medical Society in 1947 found no evidence of anticancer effects with the Gerson diet (1). The only large, retrospective review of patient survival in the literature was conducted by the Gerson Research Organization.
The American Cancer Society (ACS) warns that the Gerson method can be very harmful (9).
Purported Uses
Allergies
Arthritis
Asthma
Atherosclerosis
Cancer treatment
Cardiovascular disease
Chronic fatigue syndrome
Detoxification
Diabetes
Hypertension
Infertility
Lou Gehrig’s Disease
Migraine treatment
Multiple sclerosis
Peptic ulcers
Psoriasis
Tuberculosis
Mechanism of Action
Gerson claims he originally developed the diet to treat his migraines, but found it a successful as a treatment for skin tuberculosis and stomach cancer (7). His therapy is based on the theory that cancer is caused by alteration of cell metabolism by toxic environmental substances and food processing, which changes the sodium and potassium content of foods. Gerson’s rationale is that cancer patients have low immunity and generalized tissue damage characterized by decreased intracellular potassium to sodium (K/Na) ratios, and, when their cancer is destroyed, toxic degradation products cause coma and death. His diet increases potassium intake and minimizes sodium consumption in an effort to correct the electrolyte imbalance, repair tissue, and detoxify the liver, while coffee enemas reportedly cause dilation of bile ducts and excretion of toxic breakdown products by the liver and through the colon wall. Supplemental potassium and oxidizing thyroid enzymes are given to introduce oxidation to cancer cells and kill them. None of these claims has been substantiated by scientific research (4)(6).
This regimen has resulted in coma-inducing low levels of sodium. Case reports of deaths from repeated administration of coffee enemas indicate that the practice causes a dangerous decrease in serum electrolytes. Coffee enemas have an osmolality of 62 mOsm/kg; repeated administration increases extravascular fluid volume and may cause electrolyte imbalances and subsequent death (5).
The ease of absorption of the high volumes of raw fruit and vegetables in this diet is questionable, especially in patients with GI cancers or chemotherapy-induced mucosal damage. While elements of the Gerson diet are similar to diet recommendations made by the USDA and the American Cancer Society, metabolic diets are unsuitable for some patients with disseminated or metastatic disease, particularly of the head, neck, and gut (1).
Adverse Reactions
Common: Flu-like symptoms, loss of appetite, perspiration with foul odor, weakness, dizziness, cold sores, fever blisters, high fever, tumor pain, intestinal cramping, diarrhea, and vomiting. (The Gerson handbook claims that these adverse reactions are indicative of response) (1). Common (metabolic diet): Nutrient deficiencies (calcium, vitamins D and B12, protein), anemia, and malabsorption may result from metabolic diets. Reported:Campylobacterfetus sepsis caused by the liver injections was reported in 13 patients using the Gerson therapy between 1980-6; liver injections were subsequently eliminated from the regimen. Coma from low serum sodium (as low as 102 mEq/l) occurred in 5 of these patients (9).
Coffee enemas cause electrolyte imbalance, which has resulted in serious infections, dehydration, colitis, constipation, and death. Case Reports (Coffee enemas): Case 1: Multiple seizures and hypokalemia leading to cardiorespiratory arrest, coma, and death were reported after excessive use of coffee enemas (1-4 per hour) for a number of days. Case 2: Death attributable to fluid and electrolyte imbalance causing pleural and pericardial effusions after use of coffee enemas, 4 per day for 8 weeks (5).
References
US Congress, Office of Technology Assessment: Unconventional Cancer Treatments. Washington, DC: U.S. Government Printing Office, 1990. OTA-H-405