Cellfood

• How It Works

  Cellfood has not been shown to treat or cure cancer.

  Cellfood is a line of dietary supplements sold over the internet and in health food stores. Promoters claim that it contains minerals, enzymes, amino acids, and dissolved oxygen, which hyperoxygenates the body. Lab studies show that Cellfood has antioxidant effects, and causes some cancer cells to die. But these effects have not been shown in humans.
  Supplements with antioxidant properties are not recommended during chemotherapy and radiotherapy.

• Purported Uses

  There is no scientific evidence to support use of Cellfood for the following uses:

  • To prevent and treat cancer
  • To enhance athletic performance
• Brand Name

  Cellfood (Manufactured by Nu Science / Deutrel Industries)

• Clinical Summary

  Cellfood is a line of dietary supplements and topical preparation manufactured by NuScience Corporation. The original formula contains colloidal minerals, amino acids, enzymes and dissolved oxygen ⁽¹⁾. It is marketed as a free radical scavenger to help detoxify the body and to enhance athletic performance. Cellfood is also promoted to cancer patients based on the theory that cancer and degenerative diseases are caused by oxygen deficiency at the cellular level.

  In vitro studies show that Cellfood has antioxidant ^(2) (3) and antiproliferative effects ^(4) (5). Small studies indicate that it may alleviate symptoms of fibromyalgia ⁽⁶⁾; when combined with chelation treatment, cellfood improves oxidative status and homocysteine metabolism in patients with neurodegenerative diseases (ND) ⁽⁷⁾, as well as in patients affected by ND showing aluminium intoxication ⁽⁸⁾.

  Cellfood has not been studied in cancer patients. Supplements with antioxidant properties are not recommended during chemotherapy and radiotherapy.

• Purported Uses
  • Detoxification
  • Athletic performance enhancement
  • Cancer prevention
  • Cancer treatment
  • Fibromyalgia
• Mechanism of Action

  Cellfood demonstrated antioxidant effects in vitro ^(2) (3) and proapoptotic effects in human mesothelioma and colon cancer cells, which correlated with increased expression of tumor suppressor genes p53, p21, and p27; downregulation of the oncogenes c-myc and Bcl-2; and inhibition of activation of antiapoptotic protein kinase, Akt ⁽⁴⁾. Cellfood also showed antiproliferative effects in leukemia cells by inducing apoptosis and by altering the metabolism of cancerous cells through regulating the hypoxia inducible factor 1 alpha (HIF-1α) and glucose transporter 1 (GLUT-1) ⁽⁵⁾.

• Herb-Drug Interactions

  Theoretically, antioxidants can decrease the efficacy of certain chemotherapy drugs that rely on the generation of free radicals for their cytotoxic effects.

• References

  1. Nuscience Corporation.www.cellfood.com. Accessed August 12, 2019.

  2. Ferrero E, Fulgenzi A, Belloni D, Foglieni C, Ferrero ME. Cellfood™ improves respiratory metabolism of endothelial cells and inhibits hypoxia-induced reactive oxygen species (ros) generation. J Physiol Pharmacol. 2011 Jun;62(3):287-93.

  3. Benedetti S, Catalani S, Palma F, Canestrari F. The antioxidant protection of CELLFOOD against oxidative damage in vitro. Food Chem Toxicol. 2011 Sep;49(9):2292-8.

  4. Nuvoli B, Santoro R, Catalani S, et al. CELLFOOD™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways. J Exp Clin Cancer Res. 2014 Mar 5;33:24.

  5. Catalani S, Carbonaro V, Palma F, et al. Metabolism modifications and apoptosis induction after Cellfood™ administration to leukemia cell lines.J Exp Clin Cancer Res. 2013 Sep 9;32:63.

  6. Nieddu ME, Menza L, Baldi F, Frediani B, Marcolongo R. [Efficacy of Cellfood’s therapy (deutrosulfazyme) in fibromyalgia]. [Article in Italian] Reumatismo. 2007 Oct-Dec;59(4):316-21.

  7. Fulgenzi A, De Giuseppe R, Bamonti F, Ferrero ME. Improvement of oxidative and metabolic parameters by cellfood administration in patients affected by neurodegenerative diseases on chelation treatment. Biomed Res Int. 2014;2014:281510.

  8. Fulgenzi A, De Giuseppe R, Bamonti F, Vietti D, Ferrero ME. Efficacy of chelation therapy to remove aluminium intoxication. J Inorg Biochem. 2015 Nov;152:214-8.